Buprenorphine (Subutex) Hidden Knowledge

I’ve mastered my subject matter on this substance. Oral ba is low, like 10%, but it acts as a full mu agonist. Take cimetidine grapefruit juice to inhibit CYP enzyme prior. Good if u have a large script of Subutex generic!

Analogues can be procured…

Small IN lines produce more euphoria than any ROA. 8mg sublingual dose daily will partial bind to 80% of mu receptor sites.

4mg is 40%. This allows dual agonist therapy to be used. Morphine and bup combo.

If you IV, hapf life is only 3-4 hours. Reason unknown.