I love when a character generally deemed "The Strongest" by the series is in that position not because of overwhelming physical dominance or fundamentally better abilities, but rather by virtue of simply being better at what they do.

Honestly I like it more when, even if their power is simple, the "strongest" is explicitly not in that position because of pure physical might, but rather in spite of it. Probably my favorite examples of this (outside of Jojo) are King Bradley from Fullmetal Alchemist and Sato from Ajin: Demi-human.

Bradley's generally considered the strongest character outside of the literal final boss and the spiritual embodiment of natural order, yet he's just a fast, skilled swordsman who's trained all his life. He's not the physically strongest, because there's Sloth (basically Hulk but lazy), multiple chimeras, and even a few humans who'd beat him in an arm wrestling competition any day of the week. He's not the fastest because Sloth can speedblitz characters in a similar manner but with way less effort. And he's not the most durable because he's not only "just" an exceptionally hard-to-kill guy but also lacks the invincible skin of Greed or even the regeneration that any other Homunculi has. His Ultimate Eye grants greater visual acuity akin to a Byakugan but is limited by a normal field of view, letting him quickly analyze situations visually and react accordingly, yet it's up to himself to react, unlike the more blatantly broken powers of the others.

When he gets shot, it matters. And even his weapons are nothing to write home about, being regular military spadroons interspersed with the occasional knife when necessary. They're disposable and more than capable of breaking under the right stress, and without them he loses a lot of offensive capability against characters in a similar weight class like other homunculi. Yet despite all this he's one of the most feared because of his merciless, no-nonsense approach to fighting and his sheer skill and adaptability.

Sato takes his own unique approach to being the strongest for a sci fi manga, because he, a regenerating, immortal human known as an Ajin is operating on the exact same powerset every other character does. Every Ajin has the ability to regenerate upon death and a good chunk of them can summon a black "ghost" called an IBM with minor superhuman strength. This is all Ajins can do, nothing more, and the same is true with Sato.

He doesn't have any secret technique or OP Stat that puts him above everyone else, and this isn't a world where people can train to the point of dodging bullets or lifting cars, he's just human. Despite this, he manages to be a one-man army because of his gunfighting skill, ability to improvise and adapt with basically any tools on hand, out-of-the-box strategies, and sheer madness.

The man will literally game the system of his own powers so hard that he'll figure out entirely new applications nobody's considered, like turning himself into a friendly fire risk by diving in the middle of a squad of police or turning grenades into close-quarter weapons. And those aren't even close to the craziest things he does. Because of all this Sato is on a different level any other one person in the series, even when working with the same tools.

I find this type of "Strongest" character interesting because they manage to dominate despite not having abilities that allow them to completely breeze through situations like others might, having to not only put the work in to become as feared as they have, but constantly adapt and respond to situations that let them show of their skill and tactical ability rather than simply bulldozing through with higher numbers. Multiple characters could snap Bradley like a twig or dice him up if he gave them the chance, yet he never does. A well-timed car bomb with followup tranquilizers could easily put Sato out of the fight, yet he makes sure to never put himself in positions like that. It's not sheer that allows them to dominate their opponents, but rather how they use what they have.