marathon/long distance runners, what's the best neighborhood (east of the 405) for running?

i'm moving back to LA from SF. here we have lots of great parks/stoplight free zones that make long runs super easy. i obviously would prefer somewhere on the westside because you have access to Strand/Marvin Braud Bike Path, but that's far away from where lots of my friends are in weho/echo park/silver lake. i don't love driving to runs, and all things being equal would like being on the westside for the longer paths. but also my therapist would be mad at me for considering solely that and not proximity to my social network lol

what neighborhoods that aren't on the westside are good for getting long runs in (10+ miles) that don't have incessant stoplights? i used to live in weho which i loved but you are so stuck in the grid that i found it hard to really get into a groove over a longer distances since there were so many stoplights.